Today, January 10, 2017, Time Magazine published an article on their website that Natural Progesterone stopped early miscarriage. Stephenson, MD associated with the University of Illinois demonstrated that women that took Natural Progesterone 100-200 mg of micronized vaginally every 12 hours improved their pregnancy success. These women were selected because they had several previous miscarriages and had high nCyclinE blood levels. High nCyclinE blood levels were associated with a higher chance of early miscarriage.

Stephenson, MD in the Time Magazine article says that oral progesterone, and topical progesterone cream can also be used to prevent miscarriage. The Time Magazine article is here if the link is still live. And here is a link to the original article.[1]

A previous randomized study of the use of Progesterone to prevent miscarriage found no effect of progesterone to prevent miscarriage.[2] However, in my opinion, the researcher of this study did NOT USE THE PROGESTERONE CORRECTLY. He gave 400 mg of vaginal micronized progesterone ONCE A DAY. The progesterone must be given at least TWICE A DAY EVERY 12 hours. John Lee, MD in his book, "What Your Doctor May Not Tell You About Breast Cancer" made the point that the levels go up and down in the body with topical progesterone in about 7 hours. Therefore, it is important to take progesterone EVERY 12 HOURS or EVERY 8 HOURS. Otherwise, the dropping progesterone levels in the body will signal to create a miscarriage.

1. Mary D. Stephenson, M.D., M.Sc., Dana McQueen, M.D., M.A.S., Michelle Winter, M.D., Harvey J. Kliman, M.D., Ph.D. Luteal start vaginal micronized progesterone improves pregnancy success in women with recurrent pregnancy loss, Fertility and Sterility, Jan. 9, 2017.

2. Coomarasamy A, Williams H, Truchanowicz E, et al, A Randomized Trial of Progesterone in Women With Recurrent Miscarriages, N Engl J Med 2015;373:2141-2148.